Multiscale phenomena related to diabetic foot.

Diabetes is a group of metabolic diseases causing a system disorder, i.e.; it cannot be explained or understood by phenomena on single material scale. The diabetic foot is studied as flexible multibody structure by nonlinear finite element method. The physical and geometrical multiscale heterogeneity is solved by multilevel finite element approach. The diabetic tissue is described by internal coordinate's formalism, as complex multiscale process in tissue. The accompanying problem of the axisymetric wound healing is solved numerically. Some results related to foot deformity, stress and strain concentration and wound healing are presented.